Donald Hedeker's chief expertise is in the development and use of advanced statistical methods for clustered and longitudinal data, with particular emphasis on mixed-effects models. He is the primary author of several freeware computer programs for mixed-effects analysis. With Robert Gibbons, Don is the author of the text “Longitudinal Data Analysis,” published by Wiley in 2006. More recently, he has developed methods and software for analysis of intensive longitudinal data, which are data with many measurements over time, often collected using mobile devices and/or the internet. Such data are increasingly obtained by researchers in many research areas, for example in the areas of mobile health (mHealth) and ecological momentary assessment (EMA) studies. He is an associate editor for Statistics in Medicine.
University of Chicago
Chicago
PhD - Quantitative Psychology
1989
University of Chicago
Chicago
BA - Economics
1980
The Mean and Variability of Morning Hour Activity Over 2-3?Days Predict 5-Year Mortality and Frailty Risk in a National Sample of Older Adults.
The Mean and Variability of Morning Hour Activity Over 2-3?Days Predict 5-Year Mortality and Frailty Risk in a National Sample of Older Adults. J Am Geriatr Soc. 2026 Sep 17.
PMID: 42754817
Association Between Meeting 24-Hour Movement Behavior Guidelines and Adiposity Among Portuguese Children.
Association Between Meeting 24-Hour Movement Behavior Guidelines and Adiposity Among Portuguese Children. Pediatr Exerc Sci. 2026 Aug 19; 1-7.
PMID: 42618031
Optimizing Multicomponent Interventions to Improve Child Mental Health Following Reintegration From Institutions: Protocol for a Factorial Randomized Trial.
Optimizing Multicomponent Interventions to Improve Child Mental Health Following Reintegration From Institutions: Protocol for a Factorial Randomized Trial. JMIR Res Protoc. 2026 07 16; 15:e93033.
PMID: 42466725
Fast Estimation and Valid Statistical Inference for Mixed-Effect Location-Scale Models Using Variational Inference.
Fast Estimation and Valid Statistical Inference for Mixed-Effect Location-Scale Models Using Variational Inference. Stat Med. 2026 Jun; 45(13-14):e70640.
PMID: 42310838
Suboptimal Levothyroxine Treatment is Associated with Increases in Mean Blood Pressure and Blood Pressure Variability.
Suboptimal Levothyroxine Treatment is Associated with Increases in Mean Blood Pressure and Blood Pressure Variability. J Clin Endocrinol Metab. 2026 May 19; 111(6):e1626-e1633.
PMID: 41403148
Modeling intraindividual means and variances from ecological momentary assessment data: comparing standard computational formulas to mixed-effects location-scale model estimates.
Modeling intraindividual means and variances from ecological momentary assessment data: comparing standard computational formulas to mixed-effects location-scale model estimates. J Behav Med. 2026 04; 49(2):254-274.
PMID: 42098572
Behavior change intervention targeting physical activity and diet improves stress and sleep.
Behavior change intervention targeting physical activity and diet improves stress and sleep. PLoS One. 2026; 21(3):e0343397.
PMID: 41770781
A Note on Ordinal Modeling of Smoking Rate Data.
A Note on Ordinal Modeling of Smoking Rate Data. Nicotine Tob Res. 2026 Feb 24; 28(3):397-403.
PMID: 40305323
Measuring Hypothyroidism Disease Control Using a TSH-based "Time-in-range".
Measuring Hypothyroidism Disease Control Using a TSH-based "Time-in-range". J Clin Endocrinol Metab. 2026 Jan 21; 111(2):e484-e492.
PMID: 40645612
Mixed-effects location scale modeling of stress and contextual factors on overeating: a real-world observational study.
Mixed-effects location scale modeling of stress and contextual factors on overeating: a real-world observational study. Int J Obes (Lond). 2026 Mar; 50(3):633-639.
PMID: 41559395
Sells Award for Distinguished Multivariate Research
Society of Multivariate Experimental Psychology
2022
Elected Member, Society of Multivariate Experimental Psychology
Society of Multivariate Experimental Psychology
2016
Long-Term Excellence Award, Health Policy Statistics Section ASA
Health Policy Statistics Section ASA
2015
Elected Member, International Statistical Institute
International Statistical Institute
2015
Fellow, American Statistical Association
American Statistical Association
2000