People

Dezheng Huo, PhD

Dr. Huo’s research interests focus on the genetic, molecular, and environmental factors underlying etiology, prognosis, and treatment of cancers, particularly as they relate to cancer in underserved populations. His research spans across several areas of cancer epidemiology and clinical epidemiology, including:



1. Genetic epidemiology of breast cancer, particular in women of African ancestry with the use of genome-wide association and whole genome sequencing approach.



2. Environmental and lifestyle factors for breast cancer etiology in African women and risk prediction model building, and strategy for cancer screening.



3. Epigenetics and non-coding RNAs, such as microRNAs in relationship to cancer prognosis and survival.



4. Investigation of the utilization and effectiveness of cancer treatment in real world using big data.



5. Prenatal exposure to diethylstilbestrol and clear cell adenocarcinoma of vagina and cervix, as well as other health conditions in later life.



6. Health disparity in breast cancer outcomes in multiethnic patient cohort study with multi-dimensional data.

Prenatal diethylstilbestrol exposure and risk of diabetes, gallbladder disease, and pancreatic disorders and malignancies.
Troisi R, Hyer M, Titus L, Palmer JR, Hatch EE, Huo D, Aagaard KM, Strohsnitter WC, Hoover RN. Prenatal diethylstilbestrol exposure and risk of diabetes, gallbladder disease, and pancreatic disorders and malignancies. J Dev Orig Health Dis. 2020 Oct 28; 1-8.
PMID: 33112220

Racial disparities in survival outcomes among breast cancer patients by molecular subtypes.
Zhao F, Copley B, Niu Q, Liu F, Johnson JA, Sutton T, Khramtsova G, Sveen E, Yoshimatsu TF, Zheng Y, Ibraheem A, Jaskowiak N, Nanda R, Fleming GF, Olopade OI, Huo D. Racial disparities in survival outcomes among breast cancer patients by molecular subtypes. Breast Cancer Res Treat. 2020 Oct 27.
PMID: 33111220

Circulating Insulin-Like Growth Factor-1 and Risk of Total and 19 Site-Specific Cancers: Cohort Study Analyses from the UK Biobank.
Qian F, Huo D. Circulating Insulin-Like Growth Factor-1 and Risk of Total and 19 Site-Specific Cancers: Cohort Study Analyses from the UK Biobank. Cancer Epidemiol Biomarkers Prev. 2020 Nov; 29(11):2332-2342.
PMID: 32856611

Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk.
Liu J, Prager-van der Smissen WJC, Collée JM, Bolla MK, Wang Q, Michailidou K, Dennis J, Ahearn TU, Aittomäki K, Ambrosone CB, Andrulis IL, Anton-Culver H, Antonenkova NN, Arndt V, Arnold N, Aronson KJ, Augustinsson A, Auvinen P, Becher H, Beckmann MW, Behrens S, Bermisheva M, Bernstein L, Bogdanova NV, Bogdanova-Markov N, Bojesen SE, Brauch H, Brenner H, Briceno I, Brucker SY, Brüning T, Burwinkel B, Cai Q, Cai H, Campa D, Canzian F, Castelao JE, Chang-Claude J, Chanock SJ, Choi JY, Christiaens M, Clarke CL. Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk. Sci Rep. 2020 06 16; 10(1):9688.
PMID: 32546843

Guidelines for Reporting of Figures and Tables for Clinical Research in Urology.
Vickers AJ, Assel MJ, Sjoberg DD, Qin R, Zhao Z, Koyama T, Botchway A, Wang X, Huo D, Kattan M, Zabor EC, Harrell F. Guidelines for Reporting of Figures and Tables for Clinical Research in Urology. BJU Int. 2020 07; 126(1):14-25.
PMID: 32542947

Propensity score analysis of the prognostic value of genomic assays for breast cancer in diverse populations using the National Cancer Data Base.
Ibraheem A, Olopade OI, Huo D. Propensity score analysis of the prognostic value of genomic assays for breast cancer in diverse populations using the National Cancer Data Base. Cancer. 2020 Sep 01; 126(17):4013-4022.
PMID: 32521056

Guidelines for Reporting of Figures and Tables for Clinical Research in Urology.
Vickers AJ, Assel MJ, Sjoberg DD, Qin R, Zhao Z, Koyama T, Botchway A, Wang X, Huo D, Kattan M, Zabor EC, Harrell F. Guidelines for Reporting of Figures and Tables for Clinical Research in Urology. Eur Urol. 2020 Jul; 78(1):97-109.
PMID: 32451178

Guidelines for Reporting of Figures and Tables for Clinical Research in Urology.
Vickers AJ, Assel MJ, Sjoberg DD, Qin R, Zhao Z, Koyama T, Botchway A, Wang X, Huo D, Kattan M, Zabor EC, Harrell F. Guidelines for Reporting of Figures and Tables for Clinical Research in Urology. J Urol. 2020 07; 204(1):121-133.
PMID: 32441187

Guidelines for Reporting of Figures and Tables for Clinical Research in Urology.
Vickers AJ, Assel MJ, Sjoberg DD, Qin R, Zhao Z, Koyama T, Botchway A, Wang X, Huo D, Kattan M, Zabor EC, Harrell F. Guidelines for Reporting of Figures and Tables for Clinical Research in Urology. Urology. 2020 Aug; 142:1-13.
PMID: 32446805

Clinical evaluation of germline polymorphisms associated with capecitabine toxicity in breast cancer: TBCRC-015.
O'Donnell PH, Trubetskoy V, Nurhussein-Patterson A, Hall JP, Nath A, Huo D, Fleming GF, Ingle JN, Abramson VG, Morrow PK, Storniolo AM, Forero A, Van Poznak C, Liu MC, Chang JC, Merkel DE, Peppercorn JM, Rugo HS, Dees EC, Hahn OM, Hoffman PC, Rosner GL, Huang RS, Ratain MJ, Cox N, Olopade OI, Wolff AC, Dolan ME, Nanda R. Clinical evaluation of germline polymorphisms associated with capecitabine toxicity in breast cancer: TBCRC-015. Breast Cancer Res Treat. 2020 Jun; 181(3):623-633.
PMID: 32378051

View All Publications

Study section of P01
NIH/NCI
2019

Study section of R01/R21
NIH/NCI
2018 - 2020

Study section of U01, H3Africa
NIH/NHGRI
2017

Study section of P01
NIH/NCI
2017

Runner-up in the Up For A Challenge – Stimulating Innovation in Breast Cancer Genetic Epidemiology
National Cancer Institute
2016

Study section of U54
NIH/NIMHD
2015

Distinguished Investigator Junior Award
University of Chicago
2014

Breast Cancer Research Program study section
U.S. Army Medical Research and Materiel Command
2013 - 2014

Breast Cancer Research Program study section
U.S. Army Medical Research and Materiel Command
2010

Breast Cancer Research Program study section
U.S. Army Medical Research and Materiel Command
2008

Delta Omega
National Honor Society in Public Health
2005

Haenszel Award for Excellence in Research
University of Illinois at Chicago
2005

Student Travel Award
University of Illinois at Chicago
2000