People

Brian Chih-Hung Chiu, PhD

Dr. Chiu investigates the causes and outcomes of lymphoma and multiple myeloma in racial/ethnic and geographic diverse population using integrated modern molecular techniques and epidemiologic approaches. His main focus areas are: (1) studying modifiable nutritional, lifestyle, and environmental factors that are responsible for causing lymphoma and multiple myeloma, (2) identifying lifestyle, tumor, and treatment-related factors that influence survival, treatment response disparities, and outcomes of patients using cohorts of lymphoma and multiple myeloma patients as well as real world big data, and (3) developing novel epigenetics-based biomarkers for prognostication and management of patients using a liquid biopsy approach. He is also an active researcher in large international consortia, including the International Lymphoma Epidemiology Consortium (InterLymph), International Multiple Myeloma Consortium (now InterLymph-Myeloma Working Group) where he served as its chair in 2013, and the AsiaLymph.

Racial differences in treatment and outcomes in multiple myeloma: a multiple myeloma research foundation analysis.
Derman BA, Jasielec J, Langerman SS, Zhang W, Jakubowiak AJ, Chiu BC. Racial differences in treatment and outcomes in multiple myeloma: a multiple myeloma research foundation analysis. Blood Cancer J. 2020 Aug 07; 10(8):80.
PMID: 32770051

Variability in Cytogenetic Testing for Multiple Myeloma: A Comprehensive Analysis From Across the United States.
Yu Y, Brown Wade N, Hwang AE, Nooka AK, Fiala MA, Mohrbacher A, Peters ES, Pawlish K, Bock C, Van Den Berg DJ, Rand KA, Stram D, Conti DV, Auclair D, Colditz GA, Mehta J, Haiman CA, Terebelo H, Janakiraman N, Singhal S, Chiu B, Vij R, Bernal-Mizrachi L, Zonder JA, Huff CA, Lonial S, Orlowski RZ, Cozen W, Ailawadhi S. Variability in Cytogenetic Testing for Multiple Myeloma: A Comprehensive Analysis From Across the United States. JCO Oncol Pract. 2020 Oct; 16(10):e1169-e1180.
PMID: 32469686

Self-reported health and survival in older patients diagnosed with multiple myeloma.
Nabulsi NA, Alobaidi A, Talon B, Asfaw AA, Zhou J, Sharp LK, Sweiss K, Patel PR, Ko NY, Chiu BC, Calip GS. Self-reported health and survival in older patients diagnosed with multiple myeloma. Cancer Causes Control. 2020 Jul; 31(7):641-650.
PMID: 32356139

Targets of biologic disease-modifying antirheumatic drugs and risk of multiple myeloma.
Calip GS, Patel PR, Sweiss K, Wu Z, Zhou J, Asfaw AA, Adimadhyam S, Lee TA, Chiu BC. Targets of biologic disease-modifying antirheumatic drugs and risk of multiple myeloma. Int J Cancer. 2020 Sep 01; 147(5):1300-1305.
PMID: 31997371

A meta-analysis of genome-wide association studies of multiple myeloma among men and women of African ancestry.
Du Z, Weinhold N, Song GC, Rand KA, Van Den Berg DJ, Hwang AE, Sheng X, Hom V, Ailawadhi S, Nooka AK, Singhal S, Pawlish K, Peters ES, Bock C, Mohrbacher A, Stram A, Berndt SI, Blot WJ, Casey G, Stevens VL, Kittles R, Goodman PJ, Diver WR, Hennis A, Nemesure B, Klein EA, Rybicki BA, Stanford JL, Witte JS, Signorello L, John EM, Bernstein L, Stroup AM, Stephens OW, Zangari M, Van Rhee F, Olshan A, Zheng W, Hu JJ, Ziegler R, Nyante SJ, Ingles SA, Press MF, Carpten JD, Chanock SJ, Mehta J, Colditz GA, Wolf J, Martin TG, Tomasson M, Fiala MA, Terebelo H, Janakiraman N, Kolonel L, Anderson KC, Le Marchand L, Auclair D, Chiu BC, Ziv E, Stram D, Vij R, Bernal-Mizrachi L, Morgan GJ, Zonder JA, Huff CA, Lonial S, Orlowski RZ, Conti DV, Haiman CA, Cozen W. A meta-analysis of genome-wide association studies of multiple myeloma among men and women of African ancestry. Blood Adv. 2020 01 14; 4(1):181-190.
PMID: 31935283

Depressive symptoms, mental health-related quality of life, and survival among older patients with multiple myeloma.
Alobaidi A, Nabulsi NA, Talon B, Asfaw AA, Zhou J, Sharp LK, Sweiss K, Patel PR, Ko NY, Chiu BC, Calip GS. Depressive symptoms, mental health-related quality of life, and survival among older patients with multiple myeloma. Support Care Cancer. 2020 Sep; 28(9):4097-4106.
PMID: 31872292

Menstrual and reproductive factors, and hormonal contraception use: associations with non-Hodgkin lymphoma in a pooled analysis of InterLymph case-control studies.
Kane EV, Roman E, Becker N, Bernstein L, Boffetta P, Bracci PM, Cerhan JR, Chiu BC, Cocco P, Costas L, Foretova L, Holly EA, La Vecchia C, Matsuo K, Maynadie M, Sanjose S, Spinelli JJ, Staines A, Talamini R, Wang SS, Zhang Y, Zheng T, Kricker A. Menstrual and reproductive factors, and hormonal contraception use: associations with non-Hodgkin lymphoma in a pooled analysis of InterLymph case-control studies. Ann Oncol. 2012 Sep; 23(9):2362-2374.
PMID: 32018711

Racial disparities in Hodgkin's lymphoma: a comprehensive population-based analysis.
Evens AM, Antillón M, Aschebrook-Kilfoy B, Chiu BC. Racial disparities in Hodgkin's lymphoma: a comprehensive population-based analysis. Ann Oncol. 2012 Aug; 23(8):2128-2137.
PMID: 32018473

Mediation analyses of socioeconomic factors determining racial differences in the treatment of diffuse large B-cell lymphoma in a cohort of older adults.
Guadamuz JS, Ozenberger K, Qato DM, Ko NY, Saffore CD, Adimadhyam S, Cha AS, Moran KM, Sweiss K, Patel PR, Chiu BC, Calip GS. Mediation analyses of socioeconomic factors determining racial differences in the treatment of diffuse large B-cell lymphoma in a cohort of older adults. Medicine (Baltimore). 2019 Nov; 98(46):e17960.
PMID: 31725657

Prognostic implications of 5-hydroxymethylcytosines from circulating cell-free DNA in diffuse large B-cell lymphoma.
Chiu BC, Zhang Z, You Q, Zeng C, Stepniak E, Bracci PM, Yu K, Venkataraman G, Smith SM, He C, Zhang W. Prognostic implications of 5-hydroxymethylcytosines from circulating cell-free DNA in diffuse large B-cell lymphoma. Blood Adv. 2019 10 08; 3(19):2790-2799.
PMID: 31570490

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Chair
International Multiple Myeloma Consortium
2013

Delta Omega Honorary Society in Public Health
Alpha Phi Chapter
2009

Outstanding alumni
University of Iowa College of Public Health
2006